Properties
Description
Riluzole, soluble in DMSO and ethanol and insoluble in water, blocks sodium channels, affecting the action potential propagation in neurons and muscle cells, crucial for neurological and muscular function. It targets glutamate release, NMDA receptor, and sodium channel.
Molecular Formula
C8H5F3N2OS
Targets
Glutamate release; nMDA receptor; Sodium channel
Solubility
DMSO: 42 mg/mL (179.33 mM); Water: Insoluble; Ethanol: 42 mg/mL (179.33 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Riluzole serves as a sodium channel inhibitor, frequently employed in research focused on neuroprotective effects in studies related to amyotrophic lateral sclerosis (ALS) and other neurological disorders.