Sodium dichloroacetate

Synonym: 2156-56-1; Sodium dichloroacetate; Sodium 2,2-dichloroacetate; 2,2-Dichloroacetate sodium

MDL: MFCD00070489
CAS Number: 2156-56-1
Compound CID: 517326

Product Size

20 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Sodium dichloroacetate, a specific inhibitor of pyruvate dehydrogenase kinase (PDK), has been shown to derepress Na⁺-K⁺-2Cl^- cotransporter and a mitochondrial potassium-ion channel axis. Sodium dichloroacetate increases reactive oxygen species (ROS) generation, triggers apoptosis in cancer cells, and inhibits tumor growth. This product can be used in the research of anticancer drugs.

Molecular Weight

150.918

Molecular Formula

C₂HCl₂NaO₂

Form

White powder

Purity

≥98%

Identity

Confirmed by MS and NMR.

Stability

The product is stable for two years when stored at the recommended temperature.

Melting Point

198°C

Applications

Sodium dichloroacetate can be used in the research of anticancer drugs.

Storage

Store at 4°C. Protect from light.

Safety Information

Personal Protective Equipment

Gloves, eyeshields, N95 mask