Sodium starch phosphate, a form of starch phosphate, is typically a powder ranging from white to light yellow. It is created from the combination of starch and phosphate. This substance is widely utilized as a food additive and as an additional ingredient in medicine. Within the pharmaceutical industry, it is frequently included as part of drug formulations for oral tablets, granules, capsules, and other preparations. CD BioGlyco has been offering Pharmaceutical and Biological Analysis Services to our valued clients for numerous years, which includes our specialized Pharmaceutical Excipient Analysis Services. We offer a wide range of sodium starch phosphate analysis services to our clients.
Technology: Melting point determination, Viscosity determination, Expansion index determination
Journal: International Journal of Pharma Sciences and Research
IF: 5.8
Published: 2011
Results: This article focuses on the use of a new modified starch, starch phosphate, in the formulation development of tablets. The authors have found that the use of starch phosphate as an excipient improves the physical properties and drug-release characteristics of tablets. In this paper, the starch phosphate was also analyzed and characterized. After characterization, it was concluded that starch phosphate is a white, crystalline, non-hygroscopic powder that can be easily ground into particles of different sizes. Phosphoric acid starch was insoluble in water, in aqueous solutions of acidic and alkaline pH, and in a variety of organic solvents. When its aqueous dispersion was heated to 100°C, phosphoric acid starch did not form a paste/gel, whereas potato starch formed a paste/gel. As a chemically modified starch, phosphate starch is insoluble in water and has good swelling and flowability, so it can be used as a carrier in solid dispersions without pasting or gelation to increase the dissolution rate of poorly soluble drugs.
Fig.2 Phosphorification is employed in the conversion of potato starch to starch phosphate. (Chowdary, et al., 2011)
CD BioGlyco offers a wide range of sodium starch phosphate analysis services to our clients, including detailed testing and reporting on the composition, purity, and quality of the substance. In addition to standard analysis services, we also provide customized solutions to meet specific client needs. Please feel free to contact us for more information.
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