SphK inhibitor SKI-II, Purity ≥98%

Synonym: 312636-16-1; SphK inhibitor; SKI II; Sphingosine kinase inhibitor II

MDL: MFCD00733553
CAS Number: 312636-16-1
Compound CID: 753704

Product Size

10 mg; 25 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SKI-II, soluble in DMSO and ethanol and insoluble in water, targets and inhibits the activity of sphingosine kinase enzymes, which play a crucial role in the sphingolipid metabolic pathway. It targets S1P receptor.

Molecular Weight

302.78

Molecular Formula

C₁₅H₁₁ClN₂OS

Targets

S1P receptor: 0.5 μM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 57 mg/mL (188.25 mM); Water: Insoluble; Ethanol: 57 mg/mL (188.25 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

SKI-II is used as a non-specific SphK inhibitor to study sphingolipid metabolism and its impact on cancer cell viability and drug resistance.