Src inhibitor Bosutinib, Purity ≥98%

Synonym: 380843-75-4; Src inhibitor; SKI-606; SKI606

MDL: MFCD07367846
CAS Number: 380843-75-4
Compound CID: 5328940

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Bosutinib, soluble in DMSO and ethanol and insoluble in water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets Abl and Src.

Molecular Weight

530.4

Molecular Formula

C₂₆H₂₉Cl₂N₅O₃

Targets

Abl: 1 nM; Src: 1.2 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 93 mg/mL (175.31 mM); Water: Insoluble; Ethanol: 2 mg/mL (3.77 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

Bosutinib is a Src inhibitor researched for its applicability in treating Src-associated malignancies.