Src inhibitor KX2-391, Purity ≥98%

Synonym: 897016-82-9; Src inhibitor; KX2391

CAS Number: 897016-82-9
Compound CID: 23635314

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

KX2-391, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets Src (Hep 3B), Src (Hep G2), Src (HuH7), and Src (PLC/PRF/5).

Molecular Weight

431.53

Molecular Formula

C₂₆H₂₉N₃O₃

Targets

Src (Hep 3B): 26 nM (GI₅₀); Src (Hep G2): 60 nM (GI₅₀); Src (HuH7): 9 nM (GI₅₀); Src (PLC/PRF/5): 13 nM (GI₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (178.43 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

KX2-391 is used to research its role in inhibiting Src, laying the groundwork for potential cancer therapies targeting this kinase.