Src inhibitor UM-164, Purity ≥98%

Synonym: 903564-48-7; Src inhibitor; DAS-DFGO-II; UM164; UM 164

CAS Number: 903564-48-7
Compound CID: 11714353

Product Size

5 mg; 10 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

UM-164, soluble in DMSO and insoluble in ethanol and water, blocks the activity of Src kinases, which are involved in various cellular processes such as growth, differentiation, and survival, and have been implicated in the progression of several cancers and other diseases. It targets c-Src, p38α, and p38β.

Molecular Weight

640.68

Molecular Formula

C₃₀H₃₁F₃N₈O₃S

Targets

c-Src: 2.7 nM (Kd); p38α; p38β

Form

Lyophilized powder

Purity

Solubility

DMSO: 85 mg/mL (132.67 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

UM-164 is utilized in studies to target Src kinase in breast cancer models, contributing to the understanding of breast cancer biology.