Stat inhibitor C188-9, Purity ≥98%

Synonym: C188-9; 432001-19-9; TTI-101; STAT3 inhibitor TTI-101; TTI101; Stat3 inhibitor c188-9; N-(1',2-Dihydroxy-[1,2'-binaphthalen]-4'-yl)-4-methoxybenzenesulfonamide; Stat inhibitor

MDL: MFCD03141581
CAS Number: 432001-19-9
Compound CID: 1324494

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

C188-9, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of STAT activation and signaling activity. It targets STAT3.

Molecular Weight

471.52

Molecular Formula

C₂₇H₂₁NO₅S

Targets

STAT3: 4.7 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (171.78 mM); Water: Insoluble; Ethanol: 5 mg/mL (10.6 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

C188-9 can be used to inhibit STAT3, providing insights for targeting STAT3-driven tumors.

Storage

Store at -20ºC.