Properties
Description
C188-9, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of STAT activation and signaling activity. It targets STAT3.
Molecular Formula
C27H21NO5S
Targets
STAT3: 4.7 nM (Kd)
Solubility
DMSO: 81 mg/mL (171.78 mM); Water: Insoluble; Ethanol: 5 mg/mL (10.6 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
C188-9 can be used to inhibit STAT3, providing insights for targeting STAT3-driven tumors.