Stat inhibitor SH-4-54, Purity ≥98%

Synonym: SH-4-54; 1456632-40-8; 4-(N-(4-Cyclohexylbenzyl)-2-((2,3,4,5,6-pentafluoro-N-methylphenyl)sulfonamido)acetamido)benzoic acid; 4-[(4-Cyclohexylphenyl)methyl-[2-[methyl-(2,3,4,5,6-pentafluorophenyl)sulfonylamino]acetyl]amino]benzoic acid; Stat inhibitor

MDL: MFCD28143917
CAS Number: 1456632-40-8
Compound CID: 72188643

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SH-4-54, soluble in DMSO and warmed ethanol and insoluble in water, is an inhibitor of STAT activation and signaling activity. It targets STAT3 and STAT5.

Molecular Weight

610.59

Molecular Formula

C₂₉H₂₇F₅N₂O₅S

Targets

STAT3: 300 nM (Kd); STAT5: 464 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 94 mg/mL (153.94 mM); Water: Insoluble; Warmed ethanol: 47 mg/mL (76.97 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

SH-4-54 is used for targeting STAT3 and STAT5 dimerization, relevant in cancer research.

Storage

Store at -20ºC.