Stat inhibitor STAT3-IN-1, Purity ≥98%

Synonym: STAT3-IN-1; 2059952-75-7; (E)-N-(4-((E)-3,5-Dimethoxystyryl)phenyl)-3-(3,4,5-trimethoxyphenyl)acrylamide; (E)-N-[4-[(E)-2-(3,5-Dimethoxyphenyl)ethenyl]phenyl]-3-(3,4,5-trimethoxyphenyl)prop-2-enamide; Stat inhibitor

CAS Number: 2059952-75-7
Compound CID: 134130166

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

STAT3-IN-1, soluble in DMSO and ethanol and insoluble in water, is an inhibitor of STAT activation and signaling activity. It targets STAT3.

Molecular Weight

475.53

Molecular Formula

C₂₈H₂₉NO₆

Targets

STAT3: 1.82 μM (In HT29 cells); STAT3: 2.14 μM (In MDA-MB 231 cells)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (170.33 mM); Water: Insoluble; Ethanol: 4 mg/mL (8.41 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

STAT3-IN-1 can be employed to inhibit STAT3 activity, useful in cancer and immune response research.