Sucrose Octaacetate Analysis Service

Sucrose Octaacetate Analysis Service

Your Satisfaction in Sucrose Octaacetate Analysis Is Our Mission

Sucrose octaacetate, a commonly used pharmaceutical excipient, is a bitter substance frequently employed as a substitute for bitter active pharmaceuticals to enhance drug acceptance and improve properties such as drug stability and bioavailability. It continues to be utilized in fundamental physiological and pharmacological studies related to taste masking and taste mechanisms and serves as a bitter substitute in pediatric taste studies. CD BioGlyco has been at the forefront of providing clients with a comprehensive Pharmaceutical and Biological Analysis Service for many years. We offer a specialized Pharmaceutical Excipient Analysis Service, which focuses on the testing and evaluation of excipients used in drug formulations.

  • We initially isolate the sucrose octaacetate components of the drug and then utilize chromatography and mass spectrometry (MS) for their separation and identification. During this process, we separate the compounds within the mixture and identify the specific compounds through liquid chromatography. Subsequently, we determine the molecular structure and composition of these compounds by measuring their mass-to-charge ratio using MS. Additionally, we further validate and characterize sucrose octaacetate with techniques such as Fourier infrared spectroscopy (FT-IR) and nuclear magnetic resonance (NMR).
  • CD BioGlyco conducts the physical property analysis of sucrose octaacetate, including its solubility, melting point, and boiling point, after determining its chemical composition and structure. Additionally, we provide a comprehensive understanding of its chemical properties such as stability and reactivity in drugs.
  • Our experts help you determine the microbial limit and heavy metal content of sucrose octaacetate. Microbial limit testing is conducted to identify the presence of bacterial and mold contamination in the excipient. Additionally, we utilize appropriate techniques to analyze the heavy metal content of the sample, ensuring its safety and compliance with required standards.

The analysis content provided for sucrose octaacetate. (CD BioGlyco)

Publication Data

Technology: FT-IR and NMR

Journal: Chemical and Biochemical Engineering Quarterly

IF: 1.5

Published: 2017

Results: This article focuses on a green synthetic approach to esterify sucrose with acetic anhydride using ultrasound-assisted radiation to obtain sucrose octa-acetylsucrose. The article characterizes sucrose octa-acetylsucrose by FT-IR and NMR spectroscopy, confirms the occurrence of the acetylation reaction, and reveals the effect of hydrophobic substitution on the sucrose molecule. In addition, the article evaluates the foaming, foam stability, emulsification, and antimicrobial properties of sucrose octaacetate.

Fig.1 Process of sucrose acetate ultrasonic synthesis.Fig.1 Synthesis of sucrose acetates using ultrasonic technology. (Petkova, et al., 2019)

Applications

  • In drug development, analysis for sucrose octaacetate are used to analyze its stability and degradation products to assess the long-term stability of pharmaceuticals.
  • The analysis of sucrose octaacetate can be used for the detection of its residues in agricultural products, as well as for the study of its decomposition and metabolism in the environment.
  • Our analysis service can be used to monitor the progress of its synthetic reaction and to analyze the final product for purity to ensure the purity and quality of the product.

Advantages

  • Our analytical procedure for sucrose octaacetate is conducted under rigorous experimental conditions to guarantee precise outcomes.
  • The analytical techniques at CD BioGlyco apply not only to the analysis of sucrose octaacetate but also to the analysis of other analogous substances and for concurrent analyses.
  • By employing non-destructive testing methods, we reduce the impact on the sample and preserve a more comprehensive set of sample data.

The team of experts at CD BioGlyco is dedicated to delivering high-quality sucrose octaacetate analysis services and ensuring the efficacy of the procedure and the accuracy of results. We are committed to meeting the analytical needs of the pharmaceutical industry and contributing to advancements in healthcare. If you need further details, please feel free to contact us.

Reference

  1. Petkova, N.; et al. "Green" synthesis of sucrose octaacetate and characterization of its physicochemical properties and antimicrobial activity. Chemical and Biochemical Engineering Quarterly. 2017, 31(4): 395-402.
This service is for Research Use Only, not intended for any clinical use.

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