Sucrose Stearate Analysis Service

Sucrose Stearate Analysis Service

Empowering Your Research with Reliable Sucrose Stearate Analysis

CD BioGlyco is committed to providing professional sucrose stearate analysis services to our clients based on our long-standing experience in Pharmaceutical Excipient Analysis Service. Our goal is to meet the needs of our clients in quality control and product development, ensuring that their products meet the highest standards. Our sucrose stearate analysis services include but are not limited to the following.

  • Our experts separate and identify the components of sucrose stearate excipients and determine their content by using chromatographic techniques such as high-performance liquid chromatography (HPLC) or gas chromatography (GC) in combination with detectors such as ultraviolet-visible (UV) or mass spectrometric detectors. We also offer information on the molecular structure through the use of nuclear magnetic resonance (NMR) and mass spectrometry (MS) techniques such as MS coupled chromatography (LC-MS) or GC-MS to support the component identification.
  • Our experts utilize thermal analysis techniques such as thermogravimetric analysis (TGA) or differential scanning calorimetry (DSC) to evaluate the thermal stability and moisture content of your samples. Additionally, we employ chromatographic techniques to monitor the decomposition products of your samples under various conditions.
  • We use cell culture models (e.g., human skin cells, mouse fibroblasts, etc.) to expose cells to different concentrations of sucrose stearate and evaluate its effects on cell growth and survival. Commonly cytotoxicity assessment methods we used include the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay and the lactate dehydrogenase(LDH) release assay. We also perform histocompatibility testing as needed to evaluate the interactions between sucrose stearate with tissues, including inflammatory responses and cell proliferation.

Our analysis content of sucrose stearate. (CD BioGlyco)

Publication

Technology: Optical microscopy and laser diffractometer

Journal: Pharmaceutics

IF: 5.4

Published: 2011

Results: This article focuses on the application of semi-solid sucrose stearate emulsions as skin delivery systems. The article investigates different types of drugs that can be dermally delivered via semi-solid sucrose stearate emulsions, including water-soluble drugs, fat-soluble drugs, and amphoteric drugs. The results showed that semi-solid sucrose stearate emulsions have good stability and transdermal properties, and can effectively deliver drugs to the deeper layers of the skin. In addition, semi-solid sucrose stearate emulsions have low irritation and good biocompatibility for long-term use. In the article, semi-solid sucrose stearate was analyzed for its physical properties and its effect on the skin drug delivery system. Besides, the authors observed a complex network structure by optical microscopy, consisting of sucrose ester/water aggregates surrounding darker oil droplets. Rheological studies showed that semi-solid sucrose stearate has a pseudoplastic or shear-thinning rheological behavior, while the addition of a drug increases its viscosity. In terms of skin drug delivery system effects, the article evaluated the drug release properties of semi-solid sucrose stearate by in vitro diffusion cell and porcine ear stripping experiments. The results showed that the drug release rate of semi-solid sucrose stearate was influenced by its microstructure and viscosity.

Fig.1 Visualizing nanoemulsions in their initial and preserved conditions by utilizing optical light microscopy.Fig.1 Visual examination of nanoemulsions in their fresh and stored states using optical light microscopy. (Klang, et al., 2011)

Applications

  • In the pharmaceutical industry, the sucrose stearate analytical techniques can be used to develop and optimize drug dosage forms. For example, the solubility and bioavailability of a drug can be optimized by analyzing the emulsifying properties of the glycoside stearate.
  • In the cosmetics industry, analysis of glycoside stearates can be used to optimize product formulations and improve product quality and performance. For example, the texture and appearance of a cosmetic product can be optimized by analyzing the emulsifying properties of the glycoside stearate.
  • Glycosidic stearate may be found in wastewater and soil, therefore the glycosidic stearate analytical technique can be utilized to assess its levels in these environments and evaluate its impact on the ecosystem.

Advantages

  • Our sucrose stearate analysis utilizes a standardized and streamlined process to efficiently and effectively analyze and measure sucrose stearate within a short timeframe, ensuring the provision of high-quality service.
  • The analytical methods at CD BioGlyco are adaptable, utilizing chromatography, spectroscopy, and MS based on the precise needs of the analysis.
  • Our advanced analytical techniques detect sucrose stearate even at low levels, ensuring accurate quantification.

Using advanced equipment and innovative methods, CD BioGlyco provides a wide range of sucrose stearate analysis services that are customized for the pharmaceutical industry. Trust us to be your partner in ensuring the quality of your pharmaceutical products through our unparalleled analytical services! If you need more details about our service, please feel free to contact us.

Reference

  1. Klang, V.; et al. Semi-solid sucrose stearate-based emulsions as dermal drug delivery systems. Pharmaceutics. 2011, 3(2): 275-306.
This service is for Research Use Only, not intended for any clinical use.

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