Syk inhibitor BAY 61-3606 dihydrochloride, Purity ≥98%

Synonym: 648903-57-5; Syk inhibitor; BAY61-3606; BAY-61-3606; BAY-613606

CAS Number: 648903-57-5
Compound CID: 11784504

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

BAY 61-3606 dihydrochloride, soluble in DMSO and insoluble in ethanol and water, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers. It targets Syk.

Molecular Weight

463.32

Molecular Formula

C₂₀H₂₀Cl₂N₆O₃

Targets

Syk: 7.5 nM (Ki)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 14 mg/mL (30.21 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

BAY 61-3606 dihydrochloride facilitates study of Syk kinase’s role in immune response and its potential as a drug target for inflammatory and auto-immune diseases.