Syk inhibitor PRT-060318, Purity ≥98%

Synonym: 1194961-19-7; Syk inhibitor; PRT 060318; PRT060318; PRT318

MDL: MFCD28155088
CAS Number: 1194961-19-7
Compound CID: 11493841

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

PRT-060318, soluble in DMSO and water and insoluble in ethanol, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers.

Molecular Weight

340.42

Molecular Formula

C₁₈H₂₄N₆O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 66 mg/mL (159.67 mM); Water: 66 mg/mL (159.67 mM); Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

PRT-060318 inhibits spleen tyrosine kinase (Syk), providing insights into therapeutic strategies for diseases like autoimmune disorders and leukemia.