Properties
Description
R112, soluble in DMSO and insoluble in ethanol and water, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers.
Molecular Formula
C16H13FN4O2
Solubility
DMSO: 61 mg/mL (195.32 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
R112 is used to inhibit Syk activity, contributing to the understanding of its role in allergic responses and inflammation.
