Properties
Description
RO9021, soluble in DMSO and ethanol and insoluble in water, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers.
Molecular Formula
C18H25N7O
Solubility
DMSO: 5 mg/mL (14.06 mM); Water: Insoluble; Ethanol: 7 mg/mL (19.69 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
RO9021 is researched to inhibit Syk, contributing to the understanding of immune and allergic response modulation.
