Properties
Description
TAK-659 hydrochloride, soluble in warmed water and insoluble in ethanol and DMSO, blocks the activity of spleen tyrosine kinase (Syk), a key protein involved in the signaling pathways of various immune cells and implicated in the pathogenesis of autoimmune diseases and certain cancers.
Molecular Formula
C17H22ClFN6O
Solubility
DMSO: Insoluble; Warmed water: 3 mg/mL (7.88 mM); Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
TAK-659 hydrochloride is investigated for its potential to modulate the immune response via Syk inhibition in disorders like lymphoma and leukemia.
