TAM receptor inhibitor LDC1267, Purity ≥98%

Synonym: 1361030-48-9; TAM receptor inhibitor; LDC 1267; LDC-1267

CAS Number: 1361030-48-9
Compound CID: 56847486

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LDC1267, soluble in warmed DMSO and warmed ethanol and insoluble in water, is a specialized compound designed to block the activity of TAM receptors, which are receptor tyrosine kinases involved in critical processes such as immune regulation, cell survival, and cancer progression. It targets Axl, Mer, and Tyro3.

Molecular Weight

560.55

Molecular Formula

C₃₀H₂₆F₂N₄O₅

Targets

Axl: 29 nM; Mer: <5 nM; Tyro3: 8 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 89 mg/mL (158.77 mM); Water: Insoluble; Warmed ethanol: 2 mg/mL (3.56 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

LDC1267 is applied to block TAM receptors, which play roles in immune regulation and cancer progression.