TAM receptor inhibitor SGI-7079, Purity ≥98%

Synonym: 1239875-86-5; TAM receptor inhibitor; SGI7079; SGI 7079

CAS Number: 1239875-86-5
Compound CID: 46870258

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

SGI-7079, soluble in DMSO and insoluble in ethanol and water, is a specialized compound designed to block the activity of TAM receptors, which are receptor tyrosine kinases involved in critical processes such as immune regulation, cell survival, and cancer progression. It targets Mer, YES, Axl, FLT3, Met, and RET.

Molecular Weight

455.53

Molecular Formula

C₂₆H₂₆FN₇

Targets

Mer; YES; Axl: 58 nM; FLT3; Met; RET

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 77 mg/mL (169.03 mM); Water: Insoluble; Ethanol: Insoluble

Identity

Confirmed by NMR/HPLC/MS.

Applications

SGI-7079 is used to inhibit TAM receptors, which is essential in studying the immune environment in cancers.