TAM receptor inhibitor UNC2881, Purity ≥98%

Synonym: 1493764-08-1; TAM receptor inhibitor; UNC 2881; UNC-2881

CAS Number: 1493764-08-1
Compound CID: 71721525

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

MSDS

Properties

Description

UNC2881, soluble in DMSO and warmed ethanol and insoluble in water, is a specialized compound designed to block the activity of TAM receptors, which are receptor tyrosine kinases involved in critical processes such as immune regulation, cell survival, and cancer progression. It targets Axl, Mer, and Tyro3.

Molecular Weight

463.58

Molecular Formula

C₂₅H₃₃N₇O₂

Targets

Axl: 360 nM; Mer: 4.3 nM; Tyro3: 250 nM

Form

Lyophilized powder

Purity

Solubility

DMSO: 80 mg/mL (172.57 mM); Water: Insoluble; Warmed ethanol: 4 mg/mL (8.62 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

UNC2881 is applied in research to block TAM receptors, which are important in cancer progression and immune activity.