Properties
Description
Tegaserod maleate, soluble in DMSO and ethanol and insoluble in water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets 5-HT2B receptor, and 5-HT4 receptor.
Molecular Formula
C16H23N5O·C4H4O4
Targets
5-HT2B receptor; 5-HT4 receptor
Solubility
DMSO: 72 mg/mL (172.47 mM); Water: insoluble; Ethanol: 7 mg/mL (16.77 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Tegaserod maleate can be used to increase the movement of food and stool through the intestines, thereby relieving symptoms of constipation.
Storage
Store at -20°C, and keep desiccated.
