Properties
Description
GW788388, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets ALK5.
Molecular Formula
C25H23N5O2
Solubility
DMSO: 15 mg/mL (35.25 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
GW788388 can be used to investigate its inhibition of TGF-β receptor I kinase and its potential applications in treating fibrotic diseases.