Properties
Description
LDN193189 HCl is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets ALK2 (C2C12 cells) and ALK3 (C2C12 cells).
Molecular Formula
C25H22N6.HCl
Targets
ALK2 (C2C12 cells): 5 nM; ALK3 (C2C12 cells): 30 nM
Identity
Confirmed by NMR/HPLC/MS.
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
LDN193189 HCl can be used to study its inhibitory effects on BMP type I receptors and their implications in developmental and disease processes.