TGF-β-Smad inhibitor LDN193189 HCl, Purity ≥98%

Synonym: 1062368-62-0; LDN193189 Hydrochloride; LDN193189 HCl; LDN-193189 HCl; LDN193189 (Hydrochloride); LDN-193189 monohydrochloride; LDN-193189 hydrochloride; TGF-β-Smad inhibitor

MDL: MFCD17392570
CAS Number: 1062368-62-0
Compound CID: 54613581

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LDN193189 HCl is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets ALK2 (C2C12 cells) and ALK3 (C2C12 cells).

Molecular Weight

442.94

Molecular Formula

C₂₅H₂₂N₆.HCl

Targets

ALK2 (C2C12 cells): 5 nM; ALK3 (C2C12 cells): 30 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Applications

LDN193189 HCl can be used to study its inhibitory effects on BMP type I receptors and their implications in developmental and disease processes.