TGF-β-Smad inhibitor LDN193189 HCl, Purity ≥98%

Synonym: 1062368-62-0; LDN193189 Hydrochloride; LDN193189 HCl; LDN-193189 HCl; LDN193189 (Hydrochloride); LDN-193189 monohydrochloride; LDN-193189 hydrochloride; TGF-β-Smad inhibitor

MDL: MFCD17392570
CAS Number: 1062368-62-0
Compound CID: 54613581

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

LDN193189 HCl is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation. It targets ALK2 (C2C12 cells) and ALK3 (C2C12 cells).

Molecular Weight

442.94

Molecular Formula

C₂₅H₂₂N₆.HCl

Targets

ALK2 (C2C12 cells): 5 nM; ALK3 (C2C12 cells): 30 nM

Form

Lyophilized powder

Purity

≥98%

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

LDN193189 HCl can be used to study its inhibitory effects on BMP type I receptors and their implications in developmental and disease processes.

Storage

Store at -20ºC.