Cat. No.: X23-10-ZQ814
TGF-β-Smad inhibitor LY2109761, Purity ≥98%
Synonym: LY2109761; 700874-71-1; LY 2109761; LY-2109761; 4-(2-((4-(2-(Pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinolin-7-yl)oxy)ethyl)morpholine; DV3HD37UBK; 4-(5,6-Dihydro-2-(2-pyridinyl)-4H-pyrrolo(1,2-b)pyrazol-3-yl)-7-(2-(4-morpholinyl)ethoxy)quinoline; TGF-β-Smad inhibitor
- MDL: MFCD12923354
- CAS Number: 700874-71-1
- Compound CID: 11655119
Product Size
5 mg; 10 mg; 25 mg; 50 mg; 100 mg
Properties
Description
LY2109761, soluble in DMSO and insoluble in ethanol and water, is a potent and specific inhibitor of TGF-β-Smad signaling pathway activation.
Molecular Formula
C26H27N5O2
Solubility
DMSO: 2 mg/mL (4.52 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
LY2109761 can be used to study its dual inhibition of TGF-β receptor I and II kinases and its implications in cancer therapy.
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