Properties
Description
Argatroban, soluble in DMSO and ethanol and insoluble in water, regulates proteolytic activity, playing a vital role in controlling blood coagulation and preventing excessive clot formation by targeting and modulating the activity of serine proteases like thrombin. It targets thrombin.
Molecular Formula
C23H36N6O5S
Targets
Thrombin: 5-39 nM (Ki)
Solubility
DMSO: 8 mg/mL (15.72 mM); Water: Insoluble; Ethanol: 5 mg/mL (9.83 mM)
Identity
Confirmed by NMR/HPLC/MS.
Applications
Argatroban focuses on inhibiting thrombin in blood coagulation research, particularly for preventing thrombosis.