TNF-α inhibitor Necrostatin 2 racemate, Purity ≥98%

Synonym: 852391-15-2; Necrostatin 2 racemate; Necrostatin 2 (racemate); Nec-1S; 5-((7-Chloro-1H-indol-3-yl)methyl)-3-methylimidazolidine-2,4-dione; 5-[(7-Chloro-1H-indol-3-yl)methyl]-3-methylimidazolidine-2,4-dione; TNF-α inhibitor

CAS Number: 852391-15-2
Compound CID: 643953

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Necrostatin 2 racemate, soluble in DMSO and ethanol and insoluble in water, is a compound that reduces inflammation by modulating apoptosis.

Molecular Weight

277.71

Molecular Formula

C₁₃H₁₂ClN₃O₂

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 52 mg/mL (187.24 mM); Water: Insoluble; Ethanol: 8 mg/mL (28.8 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

Necrostatin 2 racemate can be evaluated as a mixed enantiomer inhibitor of necroptosis, useful in cell death research.

Storage

Store at -20ºC.