Toll-like receptor agonist VTX-2337, Purity ≥98%

Synonym: Motolimod; 926927-61-9; VTX-2337; Motolimod (VTX-2337); VTX-378; VTX 2337; 2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide; Toll-like receptor agonist

MDL: MFCD28044318
CAS Number: 926927-61-9
Compound CID: 16049404

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VTX-2337, soluble in warmed DMSO and ethanol and insoluble in water, is a potent and selective active small molecule agonist of a Toll-like receptor. It targets TLR8.

Molecular Weight

458.6

Molecular Formula

C₂₈H₃₄N₄O₂

Targets

TLR8: 100 nM (EC₅₀)

Form

Lyophilized powder

Purity

≥98%

Solubility

Warmed DMSO: 48 mg/mL (104.67 mM); Water: Insoluble; Ethanol: 13 mg/mL (28.34 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

VTX-2337 can be used to study its role as an immune system modulator via TLR8 activation.