Toll-like receptor antagonist CU-CPT-9a, Purity ≥98%

Synonym: 2165340-32-7; 4-(7-Methoxyquinolin-4-yl)-2-methylphenol; 2-Methyl-4-(7-methoxy-4-quinolinyl)phenol; CU CPT 9a; CHEMBL4790706; 4-(7-Methoxy-4-quinolinyl)-2-methylphenol; 4-(7-Methoxyquinolin-4-yl)-2-methyl-phenol; Toll-like receptor antagonist

CAS Number: 2165340-32-7
Compound CID: 135567383

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

CU-CPT-9a, soluble in DMSO and ethanol and insoluble in water, is a Toll-like receptor 8 antagonist which regulates Toll-like receptor 8 signalling. It targets TLR8.

Molecular Weight

265.31

Molecular Formula

C₁₇H₁₅NO₂

Targets

TLR8: 0.5 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 51 mg/mL (192.22 mM); Water: Insoluble; Ethanol: 10 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

CU-CPT-9a is an inhibitor of CDK12/13 used to study transcriptional regulation and DNA damage response mechanisms.