Toll-like receptor antagonist IAXO-102, Purity ≥98%

Synonym: IAXO-102; 1115270-63-7; CID 25222900; (2R,3R,4S,5R,6S)-2-(Aminomethyl)-6-methoxy-4,5-di(tetradecoxy)oxan-3-ol; CHEMBL493017; SCHEMBL20239315; Toll-like receptor antagonist

CAS Number: 1115270-63-7
Compound CID: 25222900

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

IAXO-102, soluble in DMSO and ethanol and insoluble in water, is a Toll-like receptor 4 antagonist which negatively regulates Toll-like receptor 4 signalling.

Molecular Weight

585.94

Molecular Formula

C₃₅H₇₁NO₅

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 13 mg/mL (22.18 mM); Water: Insoluble; Ethanol: 85 mg/mL (145.06 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

IAXO-102 can be studied as an inhibitor of the MD2-TLR4 pathway, useful in exploring its role in sepsis and chronic inflammation.