Toll-like receptor inhibitor MD2-TLR4-IN-1, Purity ≥98%

Synonym: MD2-TLR4-IN-1; 2249801-12-3; CHEMBL4517719; N-(3-(1H-Indol-5-yl)-1H-indazol-5-yl)-2,6-dichlorobenzamide; 2,6-Dichloro-N-[3-(1H-indol-5-yl)-1H-indazol-5-yl]benzamide; Toll-like receptor inhibitor

CAS Number: 2249801-12-3
Compound CID: 138454798

Product Size

1 mg; 2 mg; 5 mg; 10 mg; 25 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

MD2-TLR4-IN-1, soluble in DMSO and ethanol and insoluble in water, is a small-molecule inhibitor of Toll-like receptor signaling.

Molecular Weight

421.28

Molecular Formula

C₂₂H₁₄Cl₂N₄O

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 81 mg/mL (192.27 mM); Water: Insoluble; Ethanol: 5 mg/mL

Identity

Confirmed by NMR/HPLC/MS.

Applications

MD2-TLR4-IN-1 can be used to study the inhibition of the MD2-TLR4 pathway, which is crucial in innate immunity and inflammatory diseases.