Toll-like receptor inhibitor VGX-1027, Purity ≥98%

Synonym: VGX-1027; 6501-72-0; GIT 27; 4,5-DIHYDRO-3-PHENYL-5-ISOXAZOLEACETIC ACID; git-27; Zenuzolac; 2-(3-Phenyl-4,5-dihydro-1,2-oxazol-5-yl)acetic acid; Toll-like receptor inhibitor

MDL: MFCD08696167
CAS Number: 6501-72-0
Compound CID: 10798271

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

VGX-1027, soluble in DMSO and ethanol and insoluble in water, inhibits Toll-like receptor signaling with immunomodulatory and anti-inflammatory activities. It targets IL1β and IL10.

Molecular Weight

205.21

Molecular Formula

C₁₁H₁₁NO₃

Targets

IL1β; IL10

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 38 mg/mL (185.17 mM); Water: Insoluble; Ethanol: 38 mg/mL (185.17 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

VGX-1027 can be used to research its anti-inflammatory properties and potentiation of TLR7 ligand-induced cytokine production.

Storage

Store at -20ºC.