TOPK inhibitor OTS964, Purity ≥98%

Synonym: OTS-964; 1338545-07-5; OTS964 hydrochloride; OTS964 (hydrochloride); OTS964; (R)-9-(4-(1-(dimethylamino)propan-2-yl)phenyl)-8-hydroxy-6-methylthieno[2,3-c]quinolin-4(5H)-one hydrochloride; TOPK inhibitor

CAS Number: 1338545-07-5
Compound CID: 89675898

Product Size

5 mg; 10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

OTS964, soluble in DMSO and ethanol and insoluble in water, is a potent and selective TOPK inhibitor. It targets TOPK.

Molecular Weight

429

Molecular Formula

C₂₃H₂₅ClN₂O₂S

Targets

TOPK: 28 nM

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 76 mg/mL (177.16 mM); Water: Insoluble; Ethanol: 1 mg/mL (2.33 mM)

Identity

Confirmed by NMR/HPLC/MS.

Stability

The product is stable for three years when stored at the recommended temperature in lyophilized powder.

Applications

OTS964 can be investigated for its role in inhibiting TOPK/PBK kinase in cancer cells.

Storage

Store at -20ºC.