Topoisomerase inhibitor, 9-Amino-CPT, Purity ≥98%

Synonym: 91421-43-1; 9-Amino-20(S)-camptothecin; (19S)-8-Amino-19-ethyl-19-hydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4,6,8,10,15(20)-heptaene-14,18-dione

MDL: MFCD00909855
CAS Number: 91421-43-1
Compound CID: 72402

Product Size

2 mg; 5 mg; 10 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

9-Amino-CPT, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

363.37

Molecular Formula

C₂₀H₁₇N₃O₄

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 23 mg/mL (63.3 mM); Water: insoluble; Ethanol: insoluble

Applications

9-Amino-CPT is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers, including colorectal cancer, lung cancer, and other solid tumors