Topoisomerase inhibitor, ABT-492, Purity ≥98%

Synonym: 189279-58-1; WQ-3034; ABT492; Delafloxacin; 1-(6-Amino-3,5-difluoropyridin-2-yl)-8-chloro-6-fluoro-7-(3-hydroxyazetidin-1-yl)-4-oxoquinoline-3-carboxylic acid

CAS Number: 189279-58-1
Compound CID: 487101

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

ABT-492, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

440.8

Molecular Formula

C₁₈H₁₂ClF₃N₄O₄

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 76 mg/mL (172.43 mM); Water: insoluble; Ethanol: insoluble

Applications

ABT-492 is a DNA damage inhibitor that plays a key role in disrupting key signaling pathways involved in tumor growth and resistance.