Topoisomerase inhibitor, Amonafide, Purity ≥98%

Synonym: 69408-81-7; AS1413; Xanafide; Quinamed; 5-Amino-2-[2-(dimethylamino)ethyl]benzo[de]isoquinoline-1,3-dione

CAS Number: 69408-81-7
Compound CID: 50515

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Amonafide, soluble in DMSO and ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

283.3

Molecular Formula

C₁₆H₁₇N₃O₂

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 51 mg/mL (179.99 mM); Water: insoluble; Ethanol: 4 mg/mL (14.11 mM)

Applications

Amonafide is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of various cancers, including leukemia and solid tumors.