Topoisomerase inhibitor, Beta-lapachone, Purity ≥98%

Synonym: 4707-32-8; ARQ-501; β-Lapachone; 2,2-Dimethyl-3,4-dihydrobenzo[h]chromene-5,6-dione

MDL: MFCD01712233
CAS Number: 4707-32-8
Compound CID: 3885

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Beta-lapachone, soluble in warmed DMSO and ethanol and insoluble in water, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase. It targets the IDO1 and Topo I.

Molecular Weight

242.27

Molecular Formula

C₁₅H₁₄O₃

Targets

IDO1: 0.44 μM; Topo I

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO (warmed): 29 mg/mL (119.7 mM); Water: insoluble; Ethanol: 9 mg/mL

Applications

Beta-lapachone is a DNA damage inhibitor that can be used for its effects on oxidative stress and DNA repair mechanisms.