Properties
Description
Camptothecin, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase. It targets the Topo I (cell-free assay).
Molecular Formula
C20H16N2O4
Targets
Topo I (Cell-free assay): 0.68 μM
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO: 3 mg/mL (8.61 mM); Water: insoluble; Ethanol: insoluble
Applications
Camptothecin is a DNA damage inhibitor that displays the significant potential to act as an effective starting point for developing derivatives like irinotecan and topotecan.
