Cat. No.: X24-08-YM068
Topoisomerase inhibitor, Dxd, Purity ≥98%
Synonym: 1599440-33-1; Exatecan derivative for ADC; N-[(10S,23S)-10-Ethyl-18-fluoro-10-hydroxy-19-methyl-5,9-dioxo-8-oxa-4,15-diazahexacyclo[14.7.1.02,14.04,13.06,11.020,24]tetracosa-1,6(11),12,14,16,18,20(24)-heptaen-23-yl]-2-hydroxyacetamide
- CAS Number: 1599440-33-1
- Compound CID: 117888634
Product Size
1 mg; 5 mg; 10 mg; 50 mg
Properties
Description
Dxd is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase. It targets the topoisomerase I.
Molecular Formula
C26H24FN3O6
Targets
Topoisomerase I: 0.31 μM (IC50)
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Stability
In its lyophilized form, the chemical remains stable for 36 months.
Quality Level
Research grade
Applications
Dxd is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of HER2-positive cancers, including breast cancer and gastric cancer.
Storage
Store at -20ºC, and keep desiccated.
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