Topoisomerase inhibitor, Irinotecan HCl trihydrate, Purity ≥98%

Synonym: 136572-09-3; CPT 11; Camptosar; Campto; Irinotecan; [(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate; trihydrate; hydrochloride

MDL: MFCD01862255
CAS Number: 136572-09-3
Compound CID: 60837

Product Size

200 mg; 500 mg; 1 g; 2 g

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Irinotecan HCl trihydrate, soluble in DMSO, water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

677.2

Molecular Formula

C₃₃H₃₈N₄O₆·HCl·₃H₂O

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 92 mg/mL (135.86 mM); Water: 1 mg/mL (1.47 mM); Ethanol: 6 mg/mL (8.85 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Irinotecan HCl trihydrate is a DNA damage inhibitor that plays a key role in inhibiting topoisomerase I, thereby interfering with DNA replication and promoting cancer cell death.

Storage

Store at -20ºC, and keep desiccated.