Topoisomerase inhibitor, Irinotecan, Purity ≥98%

Synonym: 97682-44-5; Camptosar; CPT-11; [(19S)-10,19-Diethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate

MDL: MFCD00866307
CAS Number: 97682-44-5
Compound CID: 60838

Product Size

100 mg; 200 mg; 500 mg; 1000 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Irinotecan, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

586.7

Molecular Formula

C₃₃H₃₈N₄O₆

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 6 mg/mL (10.23 mM); Water: insoluble; Ethanol: insoluble; In vivo: 30% propylene glycol, 5% Tween 80, 65% D5W, 28 mg/mL

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Irinotecan is a DNA damage inhibitor that plays a key role in DNA damage and cancer cell death.

Storage

Store at -20ºC, and keep desiccated.