Properties
Description
Marbofloxacin, soluble in warmed DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.
Molecular Formula
C17H19FN4O4
Titer
Free from inappropriate visible particulates, foreign matter, discoloration, or other defects
Solubility
In vitro: DMSO (warmed): 3 mg/mL (8.27 mM); Water: insoluble; Ethanol: insoluble; In vivo: 1% DMSO + 30% polyethylene glycol + 1% Tween 80, pH 4, 13 mg/mL
Applications
Marbofloxacin is a DNA damage inhibitor that plays a key role in inhibiting bacterial DNA gyrase and topoisomerase IV, which are essential for bacterial DNA replication and transcription.
