Topoisomerase inhibitor, Mitoxantrone hydrochloride, Purity ≥98%

Synonym: 70476-82-3; Novantrone; 1,4-Dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione; dihydrochloride

MDL: MFCD00242943
CAS Number: 70476-82-3
Compound CID: 51082

Product Size

50 mg; 100 mg; 250 mg; 500 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Mitoxantrone hydrochloride, soluble in DMSO and water and insoluble in ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

517.4

Molecular Formula

C₂₂H₂₈N₄O₆·2HCl

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 79 mg/mL (152.68 mM); Water: 79 mg/mL (152.68 mM); Ethanol: insoluble; In vivo: Saline, 28 mg/mL

Applications

Mitoxantrone hydrochloride is a DNA damage inhibitor that plays a key role in managing multiple sclerosis due to its immunosuppressive effects.