Topoisomerase inhibitor, Pirarubicin, Purity ≥98%

Synonym: 72496-41-4; THP-Adriamycin; THP-ADM; (7S,9S)-7-[(2R,4S,5S,6S)-4-Amino-6-methyl-5-[(2R)-oxan-2-yl]oxyoxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione

CAS Number: 72496-41-4
Compound CID: 11296583

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Pirarubicin, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

627.64

Molecular Formula

C₃₂H₃₇NO₁₂

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 6 mg/mL (9.56 mM); Water: insoluble; Ethanol: insoluble

Applications

Pirarubicin is a DNA damage inhibitor that plays a key role in inhibiting topoisomerase II, leading to DNA damage and apoptosis in cancer cells.