Topoisomerase inhibitor, Rubitecan, Purity ≥98%

Synonym: 91421-42-0; RFS 2000; RFS2000; RFS-2000; 9-Nitrocamptothecin; (19S)-19-Ethyl-19-hydroxy-8-nitro-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

MDL: MFCD06656294
CAS Number: 91421-42-0
Compound CID: 472335

Product Size

10 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Rubitecan, soluble in DMSO and insoluble in water and ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

393.35

Molecular Formula

C₂₀H₁₅N₃O₆

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 51 mg/mL (129.65 mM); Water: insoluble; Ethanol: insoluble

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Rubitecan is a DNA damage inhibitor that plays a key role in stabilizing the topoisomerase I-DNA complex, leading to DNA damage and cell death.

Storage

Store at -20ºC, and keep desiccated.