Topoisomerase inhibitor, Topotecan, Purity ≥98%

Synonym: 123948-87-8; SKF104864; SKF 104864; SKF-104864; NSC 609669; NSC609669; NSC-609669; (19S)-8-[(Dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione

MDL: MFCD00870670
CAS Number: 123948-87-8
Compound CID: 60700

Product Size

10 mg; 50 mg; 100 mg; 200 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Topotecan, soluble in DMSO, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

421.45

Molecular Formula

C₂₃H₂₃N₃O₅

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 76 mg/mL (180.33 mM)

Stability

In its lyophilized form, the chemical remains stable for 36 months.

Quality Level

Research grade

Applications

Topotecan is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of ovarian cancer, small cell lung cancer, and cervical cancer.

Storage

Store at -20ºC, and keep desiccated.