Topoisomerase inhibitor, Voreloxin hydrochloride, Purity ≥98%

Synonym: 175519-16-1; SNS-595 hydrochloride; Vosaroxin hydrochloride; AG 7352 hydrochloride; 7-[(3S,4S)-3-Methoxy-4-(methylamino)pyrrolidin-1-yl]-4-oxo-1-(1,3-thiazol-2-yl)-1,8-naphthyridine-3-carboxylic acid; hydrochloride

CAS Number: 175519-16-1
Compound CID: 10343042

Product Size

5 mg; 10 mg; 25 mg; 50 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

Voreloxin hydrochloride, soluble in DMSO and water and insoluble in ethanol, is an effective DNA damage inhibitor, that has the ability to prevent the pathway of DNA damage by inhibiting topoisomerase.

Molecular Weight

437.9

Molecular Formula

C₁₈H₂₀ClN₅O₄S

Form

Lyophilized powder

Purity

≥98%

Titer

Free from inappropriate visible particulates, foreign matter, discoloration, or other defects

Solubility

In vitro: DMSO: 1 mg/mL (2.28 mM); Water: 1 mg/mL (2.28 mM); Ethanol: insoluble

Applications

Voreloxin hydrochloride is a DNA damage inhibitor that can be studied extensively for its potential therapeutic applications in the treatment of acute myeloid leukemia (AML).