Properties
Description
Treprostinil sodium, soluble in DMSO, ethanol and water, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins. It targets DP1, DP1, EP1, EP1, EP2, EP2, EP3, EP3, EP4, EP4, and FP receptor.
Molecular Formula
C23H33NaO5
Targets
DP1: 0.6±0.1 nM (EC50); DP1: 4.4 nM; EP1: 212 nM; EP1: 285 nM (EC50); EP2: 6.2±1.2 nM (EC50); EP2: 3.6 nM; EP3: 2505 nM; EP3: 68.9 nM (EC50); EP4: 826 nM; EP4: 181 nM(EC50); FP receptor: 4680 nM
Solubility
DMSO: 75 mg/mL (181.82 mM); Water: 75 mg/mL (181.82 mM); Ethanol: 75 mg/mL (181.82 mM)
Stability
The product is stable for three years when stored at the recommended temperature in lyophilized powder.
Applications
Treprostinil sodium can be used for its ability to mimic the actions of prostacyclin, a naturally occurring substance in the body that helps to dilate blood vessels and prevent the formation of blood clots.
Storage
Store at -20°C, and keep desiccated.
