Properties
Description
Trimethobenzamide hydrochloride, soluble in DMSO, inhibits the signaling pathway between G-protein-coupled receptors (GPCRs) and G proteins.
Molecular Formula
C21H29ClN2O5
Solubility
DMSO: 81 mg/mL (190.62 mM)
Applications
Trimethobenzamide hydrochloride can be studied for its effect on blocking dopamine receptors in the chemoreceptor trigger zone of the brain, thereby reducing the activity of dopamine, which plays a key role in triggering the vomiting reflex.
