Trk receptor inhibitor 7,8-Dihydroxyflavone, Purity ≥98%

Synonym: 38183-03-8; Trk receptor inhibitor; 7,8-DHF

MDL: MFCD00006836
CAS Number: 38183-03-8
Compound CID: 1880

Product Size

5 mg; 25 mg; 50 mg; 100 mg

Price

Datasheet

Datasheet

MSDS

MSDS

Properties

Description

7,8-Dihydroxyflavone, soluble in DMSO and ethanol and insoluble in water, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkB receptor.

Molecular Weight

254.24

Molecular Formula

C₁₅H₁₀O₄

Targets

TrkB receptor: 320 nM (Kd)

Form

Lyophilized powder

Purity

≥98%

Solubility

DMSO: 44 mg/mL (173.06 mM); Water: Insoluble; Ethanol: 1 mg/mL (3.93 mM)

Identity

Confirmed by NMR/HPLC/MS.

Applications

7,8-Dihydroxyflavone is used to mimic BDNF activity, offering a research pathway for neuroprotection and therapeutic applications in neurodegenerative diseases.