Properties
Description
ANA-12, soluble in warmed DMSO and insoluble in water and ethanol, blocks the activity of tropomyosin receptor kinases, which are involved in the growth and survival of neurons. It targets TrkB.
Molecular Formula
C22H21N3O3S
Solubility
Warmed DMSO: 33 mg/mL (80.97 mM); Water: Insoluble; Ethanol: Insoluble
Identity
Confirmed by NMR/HPLC/MS.
Applications
ANA-12 is utilized for its ability to inhibit TrkB signaling, contributing to the study of neurological conditions like depression.